systematic_review
    2019
    High Quality

    The Effects of B Vitamins on Mood and Stress: A Review

    Young LM, Pipingas A, White DJ, Gauci S, Scholey A

    Published in Nutrients

    Methodology

    Systematic review of randomised controlled trials of B vitamins, alone or in complexes, on mood, stress and depressive symptoms in adults.

    Key Findings

    B-vitamin supplementation, especially at higher doses and over longer durations, showed benefit for stress and mood in healthy and at-risk populations, while effects on clinical depression were inconsistent.

    Conclusions

    B-complex supplementation appears more useful for stress and general mood than for treating diagnosed depression.

    Limitations

    Substantial heterogeneity in formulations, doses and outcome measures; several included trials were industry funded.

    Supplements Studied

    B vitamin supplementation, particularly at higher doses and over longer periods, showed benefit for mood and stress outcomes in healthy and at-risk populations.

    Outcomes Measured

    Effects of B vitamins on clinical depression were inconsistent, while benefits for general mood and stress were more reliable.

    B vitamin supplementation, particularly at higher doses and over longer periods, showed benefit for stress outcomes.

    Related Health Concerns

    Study Details

    Year:2019
    Quality Score:8/10

    Disclosures

    Funding

    University research funding

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.