rct
    2009
    High Quality

    Probiotics as adjunctive treatment for chronic rhinosinusitis: a randomized controlled trial

    Mukerji SS, Pynnonen MA, Kim HM, Singer A, Tabor M

    Published in Otolaryngology-Head and Neck Surgery

    Methodology

    Randomized double-blind placebo-controlled trial of oral Lactobacillus rhamnosus R0011 twice daily for 4 weeks with 8-week follow-up

    Key Findings

    Within-group SNOT-20 improvement at 4 weeks in the probiotic arm was not sustained and there were no significant between-group differences at 4 or 8 weeks

    Conclusions

    Oral L. rhamnosus R0011 did not improve quality of life versus placebo in chronic rhinosinusitis

    Limitations

    Single strain and dose, modest sample, short treatment period

    Supplements Studied

    Probiotics
    Probiotic

    Oral use of the probiotic strain Lactobacillus rhamnosus R0011 was not more effective than placebo.

    Related Health Concerns

    Study Details

    Year:2009
    Sample Size:77
    Duration:4 weeks
    Quality Score:7/10

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.