Lutein and zeaxanthin supplementation and association with visual function in age-related macular degeneration
Liu R, Wang T, Zhang B, Qin L, Wu C, Li Q, Ma L
Published in Investigative Ophthalmology & Visual Science
Methodology
Meta-analysis of 8 randomised controlled trials of lutein and zeaxanthin supplementation in patients with age-related macular degeneration.
Key Findings
Supplementation increased macular pigment optical density in a dose-dependent manner and improved best-corrected visual acuity and contrast sensitivity in AMD patients.
Conclusions
Lutein and zeaxanthin improve macular pigment density and some measures of visual function in established AMD.
Limitations
Small trials with heterogeneous doses and outcome measures; short follow-up; several industry funded.
Supplements Studied
Lutein and zeaxanthin supplementation increased macular pigment optical density and improved visual acuity and contrast sensitivity in AMD.
Supplementation increased macular pigment optical density in a dose-dependent manner and improved best-corrected visual acuity and contrast sensitivity in AMD patients.
Outcomes Measured
Supplementation increased macular pigment optical density and improved best-corrected visual acuity and contrast sensitivity.
Related Health Concerns
Study Details
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