rct
    1991

    Effects of phosphatidylserine in age-associated memory impairment

    Crook TH, Tinklenberg J, Yesavage J, Petrie W, Nunzi MG, Massari DC

    Published in Neurology

    Methodology

    Multicenter double-blind placebo-controlled trial of phosphatidylserine 300 mg/day for 12 weeks in older adults with age-associated memory impairment

    Key Findings

    Phosphatidylserine improved performance on memory tasks of daily life, with the largest gains in participants with the lowest baseline performance

    Conclusions

    Phosphatidylserine may modestly improve memory in age-associated memory impairment

    Limitations

    Older bovine-derived preparation; modest effect sizes; short duration

    Supplements Studied

    Phosphatidylserine improved performance on memory tasks of daily life, with the largest gains in participants with the lowest baseline performance

    Outcomes Measured

    Enhanced Memory Formation

    Phosphatidylserine improved performance on memory tasks of daily life, with the largest gains in participants with the lowest baseline performance

    Related Health Concerns

    Memory Loss
    Cognitive Decline

    Study Details

    Year:1991
    Sample Size:149
    Duration:12 weeks
    Quality Score:6/10

    Access Study

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