Effects of Ginseng on Cognitive Function: A Systematic Review and Meta-Analysis

Zeng Y, et al.

Published in Phytotherapy Research

Methodology

Systematic review and meta-analysis of randomised controlled trials of Panax ginseng supplementation reporting cognitive outcomes, with pooled standardised mean differences and subgroup/sensitivity analyses.

Key Findings

Meta-analysis of randomised trials (671 participants) found ginseng supplementation produced small improvements in some cognitive and quality-of-life measures versus placebo, but effects on global cognition were inconsistent and not robust across subgroups or sensitivity analyses.

Conclusions

Ginseng may offer minor cognitive benefits, but the evidence base is small and heterogeneous and does not support it as a treatment for cognitive impairment.

Limitations

Small pooled sample, heterogeneous ginseng species, doses and durations, varied cognitive instruments, several trials at unclear risk of bias, and possible publication bias.