meta_analysis
    2018
    High Quality

    Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized clinical trials

    Ju J, Li J, Lin Q, Xu H

    Published in Phytomedicine

    Methodology

    Cochrane-handbook-based systematic review and meta-analysis of 16 randomised clinical trials (2147 participants) of berberine for dyslipidaemia, assessing lipid parameters and adverse events

    Key Findings

    Berberine improved lipid parameters versus control, but the included trials were largely of low methodological quality.

    Conclusions

    Lipid benefits are plausible while the certainty of evidence is limited.

    Limitations

    High or unclear risk of bias in most trials; regional concentration of studies; heterogeneity.

    Supplements Studied

    Sixteen trials with total of 2147 participants were judged to be eligible and were included in the meta-analysis.

    Study Details

    Year:2018
    Sample Size:2,147
    Quality Score:8/10

    Disclosures

    Funding

    Not reported

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