systematic_review
    2003

    A review of treatment of premenstrual syndrome and premenstrual dysphoric disorder

    Kaur G, Gonsalves L

    Published in Psychoneuroendocrinology

    Methodology

    Review of pharmacological and nutritional treatments for PMS/PMDD, including calcium, magnesium and vitamin B6.

    Key Findings

    Calcium showed the most consistent benefit for irritability and mood symptoms; magnesium and B6 evidence was weaker and mixed.

    Conclusions

    Nutritional options provide modest relief of premenstrual irritability; SSRIs remain the strongest evidence.

    Limitations

    Older review; trials small and heterogeneous.

    Supplements Studied

    Calcium
    Mineral

    Calcium showed the most consistent benefit for irritability and mood symptoms; magnesium and B6 evidence was weaker and mixed.

    Magnesium
    Mineral

    Calcium showed the most consistent benefit for irritability and mood symptoms; magnesium and B6 evidence was weaker and mixed.

    Outcomes Measured

    Irritability Reduction

    Calcium showed the most consistent benefit for premenstrual irritability and mood symptoms

    Study Details

    Year:2003
    Quality Score:5/10

    Access Study

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    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.