Glutathione as an oral whitening agent: a randomized, double-blind, placebo-controlled study
Arjinpathana N, Asawanonda P
Published in Journal of Dermatological Treatment
Methodology
Randomized double-blind placebo-controlled trial of oral glutathione 500 mg/day for 4 weeks in healthy adults, measuring melanin index.
Key Findings
Melanin indices were consistently lower with glutathione than placebo at several sites, though absolute differences were small.
Conclusions
Oral glutathione produced modest reductions in skin melanin index over 4 weeks.
Limitations
Short duration, small sample, clinical relevance of melanin index change uncertain.
Supplements Studied
Melanin indices were consistently lower with oral glutathione than placebo over four weeks
Outcomes Measured
Glutathione as an oral whitening agent: a randomized, double-blind, placebo-controlled study
Study Details
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