rct
    2018

    Memory and Brain Amyloid and Tau Effects of a Bioavailable Form of Curcumin in Non-Demented Adults: A Double-Blind, Placebo-Controlled 18-Month Trial

    Small GW, Siddarth P, Li Z

    Published in American Journal of Geriatric Psychiatry

    Methodology

    Double-blind placebo-controlled 18-month trial of bioavailable curcumin 90 mg twice daily in non-demented adults with PET imaging

    Key Findings

    Curcumin improved verbal and visual memory and attention and was associated with lower amyloid and tau PET signal in the amygdala and hypothalamus

    Conclusions

    Bioavailable curcumin improved memory and mood over 18 months in non-demented adults

    Limitations

    Small single-site sample; imaging findings exploratory

    Supplements Studied

    Bioavailable curcumin improved verbal and visual memory and attention over 18 months

    Curcumin
    Compound

    Curcumin improved verbal and visual memory and attention and was associated with lower amyloid and tau PET signal in the amygdala and hypothalamus

    Outcomes Measured

    Cognitive Function

    Curcumin improved verbal and visual memory and attention over 18 months

    Related Health Concerns

    Memory Loss

    Study Details

    Year:2018
    Sample Size:40
    Duration:78 weeks
    Quality Score:6/10

    Access Study

    View on DOIView on PubMedOriginal Source

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