rct
    2021
    High Quality

    Anxiolytic effects of a galacto-oligosaccharides prebiotic in healthy females with corresponding changes in gut bacterial composition

    Johnstone N, Milesi C, Burn O, van den Bogert B, Nauta A, Hart K

    Published in Scientific Reports

    Methodology

    Four-week randomised double-blind placebo-controlled trial of 7.5 g daily GOS in healthy females aged 18-25 with high trait anxiety

    Key Findings

    GOS reduced self-reported anxiety on the STAI and increased relative abundance of Bifidobacterium compared with placebo.

    Conclusions

    GOS supplementation reduced anxiety scores in young women with elevated baseline anxiety.

    Limitations

    Narrow demographic; self-report primary outcome; industry co-authorship.

    Supplements Studied

    GOS
    Prebiotic

    Four weeks of 7.5 g daily galacto-oligosaccharides reduced self-reported anxiety and increased relative abundance of Bifidobacterium.

    Outcomes Measured

    Galacto-oligosaccharides reduced self-reported anxiety with corresponding changes in gut bacterial composition.

    Related Health Concerns

    Study Details

    Year:2021
    Sample Size:64
    Duration:4 weeks
    Quality Score:7/10

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.