meta_analysis
    2015
    High Quality

    Lutein and zeaxanthin supplementation and association with visual function in age-related macular degeneration

    Liu R, Wang T, Zhang B

    Published in Investigative Ophthalmology & Visual Science

    Methodology

    Meta-analysis of 8 RCTs of lutein/zeaxanthin supplementation in age-related macular degeneration.

    Key Findings

    Supplementation increased macular pigment optical density and improved contrast sensitivity in a dose-dependent way; best-corrected visual acuity gains were small.

    Conclusions

    Lutein and zeaxanthin improve contrast sensitivity more reliably than acuity.

    Limitations

    Heterogeneous doses; short trials; industry funding common.

    Supplements Studied

    Zeaxanthin
    Compound

    Zeaxanthin with lutein improved macular pigment density and contrast sensitivity dose-dependently.

    Lutein
    Compound

    Lutein supplementation improved macular pigment optical density and contrast sensitivity.

    Outcomes Measured

    Lutein/zeaxanthin improved macular pigment optical density and contrast sensitivity.

    Related Health Concerns

    Study Details

    Year:2015
    Sample Size:1,176
    Quality Score:7/10

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.