meta_analysis
2017
High Quality
Alginate therapy is effective treatment for GERD symptoms: a systematic review and meta-analysis
Leiman DA, Riff BP, Morgan S, Metz DC, Falk GW, French B, Umscheid CA, Lewis JD
Published in Diseases of the Esophagus
Key Findings
Alginate-containing compounds were more effective than placebo or antacids for resolution of GERD symptoms, though less effective than proton pump inhibitors.
Conclusions
Alginates are an effective option for symptomatic heartburn relief.
Limitations
Heterogeneous comparators, several industry-sponsored trials, short follow-up.
Outcomes Measured
Heartburn Relief
Primary
This study performed a systematic review and meta-analysis to examine the benefit of alginate-containing compounds in the treatment of patients with symptoms of GERD.
Related Health Concerns
Study Details
Year:2017
Duration:4 weeks
Quality Score:7/10
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