rct
    2026

    Efficacy and Safety of Low-Dose Ashwagandha Supplementation on Exercise Endurance: A Randomized, Placebo-Controlled, Double-Blind, Clinical Trial

    Prajapati H, Satia M, Shah D, Basera I

    Published in Phytotherapy Research

    Methodology

    Eight-week randomised, double-blind, placebo-controlled trial of low-dose ashwagandha root extract (30 mg/day, standardised to >15% withanolides) versus placebo in healthy adults, assessing cardiorespiratory fitness and exercise-induced fatigue

    Key Findings

    Low-dose ashwagandha supplementation was evaluated for cardiorespiratory fitness and exercise-induced fatigue in healthy adults over eight weeks, with a favourable safety profile reported.

    Conclusions

    A bioactive-optimised low-dose ashwagandha extract is a candidate for supporting exercise endurance, pending independent replication.

    Limitations

    Single trial of a proprietary branded extract, industry-linked, results need independent confirmation.

    Supplements Studied

    This study investigated the efficacy and safety of LDA supplementation on cardiorespiratory fitness and exercise-induced fatigue in healthy individuals.

    Outcomes Measured

    This study investigated the efficacy and safety of LDA supplementation on cardiorespiratory fitness and exercise-induced fatigue in healthy individuals.

    Study Details

    Year:2026
    Duration:8 weeks
    Quality Score:5/10

    Disclosures

    Funding

    Manufacturer-linked clinical trial

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.