rct
    2018

    The Long-Term Efficacy of a Galactagogue Containing Sylimarin-Phosphatidylserine and Galega on Milk Production of Mothers of Preterm Infants

    Serrao F, Corsello M, Romagnoli C, D'Andrea V

    Published in Breastfeeding Medicine

    Methodology

    Follow-up of a prospective double-blind randomised trial in mothers of infants born at 27-32 weeks gestation who received a silymarin-phosphatidylserine plus galega galactagogue or placebo in the first month after delivery; milk production assessed at 3 and 6 months.

    Key Findings

    At 3 months, exclusive human milk feeding was reported by more mothers in the galactagogue group than in the placebo group, suggesting silymarin-based supplementation helps sustain milk production in mothers of very preterm infants.

    Conclusions

    A silymarin-phosphatidylserine and galega galactagogue taken in the first month after delivery was associated with better maintenance of milk production over 3-6 months.

    Limitations

    Small sample, retrospective self-reported follow-up of the original trial, single centre, combination product prevents attribution to silymarin alone.

    Supplements Studied

    To investigate the efficacy of a galactagogue, containing Sylimarin-phosphatidylserine (SILITIDIL) and galega consumed in the first month after delivery by mothers of preterm infants, in maintaining milk production during the first 3-6 months after delivery.

    Outcomes Measured

    At the third month after delivery, exclusive human milk administration was reported by 22 mothers of GG and 12

    Study Details

    Year:2018
    Sample Size:100
    Quality Score:6/10

    Disclosures

    Funding

    Not reported

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.