systematic_review
    2021
    High Quality

    Pre-Sleep Casein Supplementation, Metabolism, and Appetite: A Systematic Review

    Dela Cruz J, Kahan D

    Published in Nutrients

    Methodology

    PRISMA systematic review of trials of pre-sleep casein on energy expenditure, lipolysis, appetite and food intake in healthy and overweight adults

    Key Findings

    Pre-sleep casein has been linked to improved muscle protein synthesis, mass and strength adaptations, but effects on overnight metabolism, lipolysis and appetite are inconsistent.

    Conclusions

    Pre-sleep casein appears metabolically safe but its non-muscular effects on metabolism and appetite remain unclear.

    Limitations

    Narrative synthesis without pooled estimates; small heterogeneous trials, mostly in young men.

    Supplements Studied

    Pre-sleep casein supplementation has been attributed to improved adaptive response by skeletal muscle to resistance training through increases in muscle protein synthesis, muscle mass, and strength.

    Outcomes Measured

    Pre-sleep casein supplementation has been attributed to improved adaptive response by skeletal muscle to resistance training through increases in muscle protein synthesis, muscle mass, and strength.

    Study Details

    Year:2021
    Quality Score:7/10

    Disclosures

    Funding

    Not specified

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.