Outcome-Specific Efficacy of Different Probiotic Strains and Mixtures in Irritable Bowel Syndrome: A Systematic Review and Network Meta-Analysis
Zhang T, et al.
Published in Nutrients
Abstract
Network meta-analysis comparing probiotic strains and mixtures for outcome-specific efficacy in IBS.
Key Findings
Network meta-analysis ranked probiotic strains by outcome; efficacy was strain- and outcome-specific and no single strain dominated across endpoints.
Conclusions
Probiotic benefit in IBS is strain-specific; generic probiotic recommendations are not supported.
Limitations
Indirect comparisons, heterogeneous outcome definitions, variable trial quality.
Supplements Studied
Network meta-analysis ranked probiotic strains by outcome; efficacy was strain- and outcome-specific and no single strain dominated across endpoints.
Efficacy in irritable bowel syndrome differs markedly between probiotic strains and mixtures depending on the outcome assessed.
Efficacy in irritable bowel syndrome differs markedly between probiotic strains and mixtures depending on the outcome assessed.
Outcomes Measured
Network meta-analysis ranked probiotic strains by outcome; efficacy was strain- and outcome-specific and no single strain dominated across endpoints.
Related Health Concerns
Study Details
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