The effects of supplementation with conjugated linoleic acid on anthropometric indices and body composition in overweight and obese subjects: A systematic review and meta-analysis
Namazi N, Irandoost P, Larijani B, Azadbakht L
Published in Critical Reviews in Food Science and Nutrition
Methodology
Systematic review and meta-analysis of 13 placebo-controlled clinical trials in overweight and obese adults
Key Findings
CLA reduced body weight (-0.52 kg), BMI (-0.23 kg/m2) and fat mass (-0.61 kg) and slightly increased lean body mass (+0.19 kg); waist circumference was unchanged.
Conclusions
CLA can slightly reduce body weight and fat mass, but the effect size is not clinically considerable.
Limitations
Substantial heterogeneity between trials; effects small and of doubtful clinical relevance.
Outcomes Measured
CLA significantly reduced body weight (WMD: -0.52 kg), BMI, FM (WMD: -0.61 kg) and increased LBM compared to the placebo group
Study Details
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