Efficacy and safety of Omija (Schisandra chinensis) extract mixture on the improvement of hyperglycemia: a randomized, double-blind, placebo-controlled trial
Kim DS, Baek HI, Ha KC, Cha YS, Park SJ
Published in Nutrients
Methodology
12-week randomized, double-blind, placebo-controlled clinical trial in 80 adults with fasting plasma glucose 100-140 mg/dL receiving an Omija (Schisandra) extract and soybean mixture or placebo, with glycemic, insulin, fructosamine, lipid and safety outcomes
Key Findings
The Schisandra-soybean mixture lowered fasting and postprandial glucose, insulin AUC, fructosamine and LDL cholesterol versus placebo with no clinically significant safety findings.
Conclusions
Supports metabolic benefit for a combination product rather than Schisandra alone.
Limitations
Combination intervention; 12 weeks; prediabetic range only; likely industry involvement.
Supplements Studied
After the intervention, the OSM group showed significantly decreased levels of FPG, PPG (30, 60 min), PPI (60 min), insulin area under the curve (AUC), fructosamine, and low-density-lipoprotein (LDL) cholesterol compared to the placebo group.
Study Details
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Disclosures
Funding
Not reported
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