Chaga mushroom-induced oxalate nephropathy
Kikuchi Y, Seta K, Ogawa Y, Takayama T, Nagata M
Published in Clinical Nephrology
Methodology
Single-patient case report with renal biopsy in a 72-year-old woman who ingested 4-5 teaspoons/day of chaga powder for 6 months
Key Findings
Renal biopsy showed diffuse tubular atrophy and interstitial fibrosis with oxalate crystals in tubular lumina and urinary sediment; hemodialysis was required.
Conclusions
Chaga mushrooms contain extremely high oxalate concentrations and prolonged high-dose intake can cause oxalate nephropathy.
Limitations
Single case; no dose-response data; concurrent malignancy and hepatectomy may have contributed to renal vulnerability.
Supplements Studied
This is the first report of a case of oxalate nephropathy associated with ingestion of Chaga mushrooms.
Study Details
Access Study
Disclosures
Funding
Not reported
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