rct
    2001

    Efficacy and safety of freeze-dried cats claw in osteoarthritis of the knee: mechanisms of action of the species Uncaria guianensis

    Piscoya J, Rodriguez Z, Bustamante SA, Okuhama NN, Miller MJ, Sandoval M

    Published in Inflammation Research

    Abstract

    Randomized placebo-controlled trial of freeze-dried Uncaria guianensis in knee osteoarthritis.

    Key Findings

    Cats claw extract reduced knee pain associated with activity within one week compared with placebo, without significant changes in knee circumference or resting pain.

    Conclusions

    Cats claw showed selective, modest symptom relief in knee osteoarthritis.

    Limitations

    Small four-week trial; limited endpoints; single extract species.

    Supplements Studied

    Cats claw extract reduced knee pain associated with activity within one week compared with placebo, without significant changes in knee circumference or resting pain.

    Outcomes Measured

    Cats claw extract reduced knee pain associated with activity within one week compared with placebo, without significant changes in knee circumference or resting pain.

    Related Health Concerns

    Study Details

    Year:2001
    Sample Size:45
    Duration:4 weeks
    Quality Score:5/10

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