Effects of perilla seed oil supplementation on leukotriene generation by leucocytes in patients with asthma associated with lipometabolism
Okamoto M, Mitsunobu F, Ashida K, Mifune T, Hosaki Y, Tsugeno H, Harada S, Tanizaki Y, Kataoka M, Niiya K, Harada M
Published in International Archives of Allergy and Immunology
Methodology
Controlled supplementation study comparing perilla seed oil with corn oil in asthmatic patients, measuring leukotriene generation and pulmonary function
Key Findings
Perilla seed oil suppressed leukotriene C4 generation by leucocytes and improved ventilatory function compared with corn oil
Conclusions
Alpha-linolenic acid rich perilla oil may modulate leukotriene-mediated airway inflammation
Limitations
Very small sample, older study, surrogate inflammatory endpoints
Supplements Studied
Perilla seed oil suppressed leukotriene C4 generation by leucocytes and improved ventilatory function compared with corn oil
Related Health Concerns
Study Details
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