rct
    2025

    Oral hyaluronic acid supplement: efficacy in skin hydration, elasticity, and wrinkle depth reduction

    Ahmed A, Kim J, Patel R

    Published in Journal of Drugs in Dermatology

    Methodology

    Randomised controlled trial of an oral hyaluronic acid supplement with objective corneometry, cutometry and wrinkle imaging endpoints

    Key Findings

    Supplementation improved hydration and elasticity measures, while wrinkle depth changes were smaller and less consistent across sites.

    Conclusions

    Oral hyaluronic acid reliably improves hydration measures; anti-wrinkle effects are more modest.

    Limitations

    Short duration; industry sponsorship; limited demographic diversity.

    Supplements Studied

    Supplementation improved hydration and elasticity measures, while wrinkle depth changes were smaller and less consistent.

    Outcomes Measured

    Supplementation improved hydration and elasticity measures, while wrinkle depth changes were smaller.

    Study Details

    Year:2025
    Sample Size:100
    Duration:12 weeks
    Quality Score:6/10

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.