Vinpocetine treatment in acute ischaemic stroke: a pilot single-blind randomized clinical trial
Feigin VL, Doronin BM, Popova TF, Gribatcheva EV, Tchervov DV
Published in European Journal of Neurology
Methodology
Single-blind randomised pilot trial of intravenous then oral vinpocetine added to standard care within 72 hours of ischaemic stroke.
Key Findings
Trends towards better functional outcome at three months in the vinpocetine group, but the trial was underpowered and not double-blind.
Conclusions
Vinpocetine appeared safe with a non-significant signal for improved outcome; definitive trials are needed.
Limitations
Small, single-blind, pilot design without adjustment for confounders.
Supplements Studied
Trends towards better three-month functional outcome were seen with vinpocetine, but the pilot trial was underpowered.
Related Health Concerns
Study Details
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