observational
    2015

    Palmitoylethanolamide in Fibromyalgia: Results from Prospective and Retrospective Observational Studies

    Del Giorno R, Skaper S, Paladini A, Varrassi G, Coaccioli S

    Published in Pain and Therapy

    Methodology

    Prospective and retrospective observational studies of PEA added to standard therapy in fibromyalgia patients

    Key Findings

    Adding PEA to duloxetine and pregabalin produced further reductions in pain scores and tender points

    Conclusions

    PEA may be a useful add-on in fibromyalgia but requires randomized confirmation

    Limitations

    Observational, unblinded, no placebo arm

    Supplements Studied

    PEA
    Compound

    Adding PEA to duloxetine and pregabalin produced further reductions in pain scores and tender points

    Outcomes Measured

    Post-Exercise Soreness Reduction

    Adding PEA to duloxetine and pregabalin produced further reductions in pain scores and tender points

    Related Health Concerns

    Fibromyalgia
    Chronic Pain
    Tender Points

    Study Details

    Year:2015
    Sample Size:80
    Duration:24 weeks
    Quality Score:4/10

    Access Study

    View on DOIView on PubMedOriginal Source

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.