Satiety and amino-acid profile in overweight women after a new treatment using a natural plant extract sublingual spray formulation
Rondanelli M, Klersy C, Iadarola P, Monteferrario F, Opizzi A
Published in International Journal of Obesity
Methodology
Two-month randomized double-blind placebo-controlled trial of a sublingual 5-hydroxytryptophan-containing plant extract spray with daily appetite visual analogue scales
Key Findings
The 5-HTP spray group reported greater satiety and reduced appetite ratings than placebo, with increased urinary 5-HIAA confirming absorption
Conclusions
Sublingual 5-HTP extract increased satiety in overweight women in a small trial
Limitations
Very small sample, proprietary formulation, subjective appetite endpoints
Supplements Studied
To test the effect on satiety of a formulation comprising plant extracts naturally containing 5-hydroxytryptophan
Related Health Concerns
Study Details
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