systematic_review
    2016
    High Quality

    Calcium channel blockers for primary Raynaud's phenomenon

    Ennis H, Hughes M, Anderson ME

    Published in Cochrane Database of Systematic Reviews

    Methodology

    Cochrane review of 7 RCTs of calcium channel blockers in primary Raynaud phenomenon.

    Key Findings

    Calcium channel blockers produced a small reduction in attack frequency, with low-quality evidence and frequent side effects.

    Conclusions

    Drug therapy for cold-induced vasospasm is only modestly effective, so trigger avoidance remains central.

    Limitations

    Small older trials; low certainty evidence.

    Supplements Studied

    Calcium
    Mineral

    Calcium channel blockers produced a small reduction in attack frequency, with low-quality evidence and frequent side effects.

    Related Health Concerns

    Cold Hands & Feet
    Cold Sensitivity

    Study Details

    Year:2016
    Sample Size:296
    Quality Score:8/10

    Access Study

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