rct
    2014

    Efficacy of a synbiotic containing Bacillus coagulans in the treatment of irritable bowel syndrome: a randomized placebo-controlled trial

    Rogha M, Esfahani MZ, Zargarzadeh AH

    Published in Gastroenterology and Hepatology from Bed to Bench

    Methodology

    Randomized, placebo-controlled trial of a B. coagulans-containing synbiotic in patients with IBS.

    Key Findings

    Abdominal pain and bloating improved significantly in the synbiotic group versus placebo, with no difference in some secondary measures.

    Conclusions

    A B. coagulans synbiotic reduced key IBS symptoms in this trial.

    Limitations

    Synbiotic formulation prevents attribution to the spore organism alone; modest sample.

    Supplements Studied

    A B. coagulans synbiotic reduced key IBS symptoms in this trial.

    Abdominal pain and bloating improved significantly in the synbiotic group versus placebo, with no difference in some secondary measures.

    Related Health Concerns

    Study Details

    Year:2014
    Sample Size:85
    Duration:12 weeks
    Quality Score:5/10

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