Therapeutic effects and safety of Rhodiola rosea extract WS 1375 in subjects with life-stress symptoms: results of an open-label study
Edwards D, Heufelder A, Zimmermann A
Published in Phytotherapy Research
Methodology
Multicentre open-label study of Rhodiola rosea extract WS 1375, 200 mg twice daily for 4 weeks, in adults with life-stress symptoms.
Key Findings
Stress symptom, fatigue, mood and quality-of-life scores improved progressively from as early as 3 days, with good tolerability.
Conclusions
Rhodiola rosea may relieve stress-related fatigue symptoms, though the absence of a placebo arm limits interpretation.
Limitations
Open-label, uncontrolled design; self-reported outcomes; manufacturer sponsored.
Supplements Studied
Stress symptom, fatigue and mood scores improved progressively over four weeks of Rhodiola rosea extract, with good tolerability.
Outcomes Measured
Fatigue and life-stress symptom scores improved progressively over four weeks of Rhodiola rosea extract.
Related Health Concerns
Study Details
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