rct
    2021

    Apple cider vinegar soaks do not alter the skin bacterial microbiome in atopic dermatitis

    Luu LA, Flowers RH, Gao Y, Wu M, Gasperino S, Kellams AL, Preston DC, Zlotoff BJ, Wisniewski JA, Zeichner SL

    Published in PLOS ONE

    Methodology

    Randomized, non-blinded, split-arm pilot study in 11 atopic dermatitis subjects and 11 healthy controls soaking one forearm in 0.5% apple cider vinegar and the other in tap water daily for 14 days, with 16S sequencing.

    Key Findings

    No difference in skin bacterial microbiome composition or diversity after 2 weeks of apple cider vinegar soaks, and no reduction in mean Staphylococcus aureus abundance (p = 0.60).

    Conclusions

    Daily soaks in 0.5% apple cider vinegar are not an effective way to alter the skin bacterial microbiome in atopic dermatitis.

    Limitations

    Small pilot sample, non-blinded design, short 2-week exposure, and microbiome endpoints rather than clinical eczema severity.

    Supplements Studied

    Our results suggest that daily soaks in 0.5% apple cider vinegar are not an effective method of altering the skin bacterial microbiome in atopic dermatitis.

    Study Details

    Year:2021
    Sample Size:22
    Duration:2 weeks
    Quality Score:6/10

    Disclosures

    Funding

    University of Virginia

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