meta_analysis
    2024
    High Quality

    Selenium Supplementation in Patients with Hashimoto Thyroiditis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

    Unknown authors

    Published in Thyroid

    Key Findings

    35 RCTs; selenium lowered TSH (SMD -0.21) and TPOAb (SMD -0.96) with adverse events comparable to control.

    Conclusions

    In people with Hashimoto thyroiditis without thyroid hormone replacement, selenium lowered TSH, TPOAb and MDA; moderate certainty.

    Supplements Studied

    Selenium
    Mineral

    In people with HT without THRT, selenium was effective and safe in lowering TSH, TPOAb, and MDA levels.

    Outcomes Measured

    B-Cell Antibody Production
    Primary

    Selenium supplementation significantly reduced thyroid peroxidase antibody titres in patients with Hashimoto thyroiditis.

    Related Health Concerns

    Thyroid Disorders

    Study Details

    Year:2024
    Quality Score:9/10

    Access Study

    View on DOIView on PubMedOriginal Source

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.