rct
    2007
    High Quality

    Suppression of human immunodeficiency virus type 1 viral load with selenium supplementation: a randomized controlled trial

    Hurwitz BE, Klaus JR, Llabre MM, Gonzalez A, Lawrence PJ, Maher KJ

    Published in Archives of Internal Medicine

    Methodology

    Double-blind placebo-controlled trial of 200 microg/day high-selenium yeast for 9 months in HIV-1 infected adults

    Key Findings

    Increases in serum selenium were associated with suppression of HIV-1 viral load and a corresponding rise in CD4 count.

    Conclusions

    Selenium supplementation that raises serum selenium suppresses HIV-1 viral burden.

    Limitations

    Effect confined to selenium responders; single-centre; modest sample.

    Supplements Studied

    Selenium
    Mineral

    Selenium supplementation suppressed HIV-1 viral load and raised CD4 count.

    Outcomes Measured

    Increases in serum selenium were associated with suppression of HIV-1 viral load and a corresponding rise in CD4 count.

    Study Details

    Year:2007
    Sample Size:262
    Duration:39 weeks
    Quality Score:8/10

    Disclosures

    Funding

    NIH / NIMH

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.