Effect of n-3 PUFA supplementation on cognitive function throughout the life span from infancy to old age: a systematic review and meta-analysis of randomized controlled trials
Jiao J, Li Q, Chu J
Published in The American Journal of Clinical Nutrition
Methodology
Meta-analysis of 34 randomised controlled trials of at least 3 months of n-3 PUFA supplementation in 12,999 participants across the lifespan
Key Findings
n-3 PUFAs improved infant cognitive development but did not promote composite memory, executive function or processing speed in children, adults or the elderly
Conclusions
Omega-3 supplementation does not reliably improve executive function outside infancy
Limitations
Heterogeneous cognitive test batteries and doses
Supplements Studied
n-3 PUFA supplements did not promote cognitive function in terms of composite memory, executive function, and processing speed domains in children, adults, or the elderly
Outcomes Measured
n-3 PUFA supplements did not promote cognitive function in terms of composite memory, executive function, and processing speed domains in children, adults, or the elderly, except for the attention domain.
n-3 PUFAs improved infant cognitive development but did not promote composite memory, executive function or processing speed in children, adults or the elderly
Study Details
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