A randomized, triple-blind, placebo-controlled, crossover study to investigate the efficacy of a single dose of AlphaWave L-theanine on stress in a healthy adult population
Evans M, et al.
Published in Neurology and Therapy
Methodology
Randomized, triple-blind, placebo-controlled crossover trial in healthy adults; a single dose was given before an acute stress task, with quantitative EEG alpha power, salivary cortisol and subjective stress scales as outcomes.
Key Findings
A single 200 mg dose of L-theanine increased frontal alpha EEG power relative to placebo during an acute stress challenge and was associated with lower subjective stress ratings, consistent with an acute calming effect.
Conclusions
A single dose of AlphaWave L-Theanine significantly increased frontal region alpha power compared to placebo in response to an acute stress challenge. These changes are indicative of relaxation in the brain and suggest a calming response.
Limitations
Acute single-dose design in healthy volunteers with surrogate EEG endpoints; no evidence about sustained or clinical anxiety benefit, and industry-supplied test ingredient.
Supplements Studied
A single dose of AlphaWave L-Theanine significantly increased frontal region alpha power compared to placebo in response to an acute stress challenge.
Related Health Concerns
Study Details
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