The Efficacy and Safety of Probiotics for Allergic Rhinitis: A Systematic Review and Meta-Analysis
Luo C, Peng S, et al
Published in Frontiers in Immunology
Methodology
Systematic review and meta-analysis of randomized placebo-controlled trials of probiotics in allergic rhinitis, pooling symptom scores, quality-of-life instruments and immunological markers.
Key Findings
Pooled randomized trials showed probiotics improved total nasal symptom scores and rhinoconjunctivitis quality-of-life scores versus placebo in allergic rhinitis, with no increase in adverse events; between-trial heterogeneity was high.
Conclusions
Probiotics appear to ameliorate allergic rhinitis symptoms and quality of life, but heterogeneity was high.
Limitations
High heterogeneity in probiotic strain, dose and duration; many small trials; inconsistent outcome instruments and possible publication bias.
Supplements Studied
Probiotic supplement seems to be effective in ameliorating allergic rhinitis symptoms and improving the quality of life, but there is high heterogeneity in some results after subgroup analysis.
Related Health Concerns
Study Details
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This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.