meta_analysis
    2019

    Effect of oral L-citrulline on brachial and aortic blood pressure defined by resting status: evidence from randomized controlled trials

    Mahboobi S, Tsang C, Rezaei S, Jafarnejad S

    Published in Nutrition & Metabolism

    Methodology

    Meta-analysis of randomized controlled trials of oral L-citrulline on brachial and aortic blood pressure stratified by resting status.

    Key Findings

    Effects on resting brachial blood pressure were small and largely non-significant; reductions were more apparent in aortic and non-resting measurements.

    Conclusions

    Blood pressure benefits of L-citrulline are inconsistent and depend on measurement conditions.

    Limitations

    Few trials per subgroup, heterogeneity in dose and duration, largely healthy or pre-hypertensive samples.

    Supplements Studied

    L-Citrulline
    Amino Acid

    Effects on resting brachial blood pressure were small and largely non-significant.

    Related Health Concerns

    Study Details

    Year:2019
    Sample Size:200
    Duration:8 weeks
    Quality Score:6/10

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