observational
    2002

    Treatment of melasma with Pycnogenol

    Ni Z, Mu Y

    Published in Phytotherapy Research

    Methodology

    Open-label 30-day trial of Pycnogenol 75 mg/day in women with melasma, measuring pigmented lesion area and intensity.

    Key Findings

    Average melasma area and pigmentary intensity decreased significantly, with no notable adverse effects.

    Conclusions

    Pycnogenol showed benefit for melasma in an uncontrolled setting.

    Limitations

    No placebo control or blinding; single-arm design; older study.

    Supplements Studied

    Average melasma area and pigmentary intensity decreased significantly, with no notable adverse effects.

    Outcomes Measured

    Hyperpigmentation Reduction

    Treatment of melasma with Pycnogenol

    Related Health Concerns

    Melasma

    Study Details

    Year:2002
    Sample Size:30
    Duration:4 weeks
    Quality Score:4/10

    Access Study

    View on DOIView on PubMedOriginal Source

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