symptom
    Immune

    Recurring Infections

    Frequent viral or bacterial infections indicating immune weakness.

    TL;DR

    Adults average 2-3 colds a year, and childcare exposure or poor sleep can double that — context explains most “always sick” patterns. When infections genuinely outpace circumstances, the checkable causes are vitamin D deficiency (with strong supplementation trial data), iron deficiency, undiagnosed diabetes, and chronic sleep deprivation. Vitamin D has good trial evidence for reducing respiratory infections in the deficient. Recurrent infections at unusual sites need immune assessment.

    Overview

    Infections that keep returning — repeated colds, sinus infections, urinary infections, or skin infections — beyond what circumstances explain. Most reflect exposure and habits rather than immune failure, but a genuine pattern warrants checking for the common, correctable causes: vitamin D deficiency, iron deficiency, diabetes, and poor sleep.

    Root Causes

    Evidence synthesis: Sleep is the most modifiable immune lever — a landmark study found adults sleeping under 6 hours were over 4x more likely to catch a cold after viral exposure than those sleeping 7+. Vitamin D supplementation has meta-analytic evidence (Martineau et al., individual-patient data across 25 RCTs) showing reduced respiratory infections, with the strongest effect in people who were deficient. Iron deficiency impairs immune cell function and is a common, testable cause, particularly in menstruating women. Undiagnosed or poorly controlled diabetes elevates infection risk measurably — recurrent skin or urinary infections are a classic first presentation. Smoking and chronic alcohol use impair respiratory and systemic immunity. True primary immune deficiencies are rare but are flagged by specific patterns: recurrent pneumonia, unusual organisms, or infections requiring IV antibiotics.

    How It's Diagnosed

    When to See a Doctor

    See a clinician for more than 4 ear or sinus infections, 2 pneumonias, or 2 deep-tissue infections in a year, for infections needing intravenous antibiotics, or for poor wound healing with weight loss.

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    Supporting Research

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    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.