Herb

    Yarrow

    Achillea millefolium

    TL;DR

    Yarrow has a long battlefield reputation for stopping bleeding and calming digestion, credible anti-inflammatory chemistry, and essentially no modern randomized evidence in humans.

    Ideal For

    • Traditional topical wound care in people without Asteraceae allergy

    Avoid If

    • You are pregnant
    • You react to ragweed, chamomile or chrysanthemum

    Frequently Asked Questions

    What is yarrow used for?
    Achillea millefolium is a traditional wound and digestive herb, used for minor bleeding, cramping and poor appetite.
    Is there human evidence?
    Controlled trials are almost absent. The pharmacology - flavonoids, sesquiterpene lactones, and an antispasmodic effect in tissue models - is reasonably characterised, but that is not the same as clinical proof.
    What dose is traditional?
    Roughly 2-4 g/day of dried herb as a tea, or a tincture equivalent, taken before meals for digestive use.
    Can it be used on wounds?
    Traditionally yes, as a poultice. For anything beyond a minor graze, use proper wound care and see a clinician.
    Who should avoid it?
    People who are pregnant - it has traditional uterine-stimulant use - and anyone allergic to the daisy family, where cross-reactivity is common.
    Any interactions?
    Theoretical additive effects with anticoagulants and sedatives. Photosensitivity has also been reported with topical use.

    Overview

    Yarrow contains sesquiterpene lactones, flavonoids including apigenin and luteolin, and an essential oil rich in chamazulene — a chemistry that overlaps substantially with chamomile. In vitro and animal work supports antispasmodic activity on intestinal smooth muscle, anti-inflammatory cytokine suppression, choleretic effects and modest antimicrobial activity, and rodent wound-healing models show accelerated closure with topical extract. The human record is where it thins out sharply. A small trial of topical yarrow for episiotomy healing reported reduced pain and better wound scores, and a handful of small studies in dysmenorrhea and gastrointestinal complaints suggest symptom benefit, but sample sizes are in the dozens and blinding is inconsistent. The name Achillea comes from the legend that Achilles carried it to treat soldiers' wounds, and topical hemostatic use is the most historically consistent application. Yarrow is in the Asteraceae family, so people allergic to ragweed, chamomile or chrysanthemum can react to it, and thujone in the essential oil makes prolonged high-dose internal use inadvisable.

    How It Works

    • Sesquiterpene lactones and flavonoids suppress inflammatory cytokine signalling
    • Apigenin and luteolin relax intestinal smooth muscle
    • Astringent tannins support topical hemostatic and wound-closure effects

    Quick Facts

    • Named after Achilles for battlefield wound use
    • Asteraceae family — cross-reacts with ragweed and chamomile allergy
    • Contains thujone; avoid prolonged high-dose internal use

    Benefits & Outcomes

    No linked outcomes yet. Research is ongoing.

    Supporting Research
    4 studies

    Effect of Achillea millefolium on relief of primary dysmenorrhea: a double-blind randomized clinical trial

    Score: 6/10
    2015
    rct
    n=68

    Jenabi E, Fereidoony B

    Pain severity scores decreased significantly more in the Achillea millefolium group than placebo over two menstrual cycles.

    View source

    Pharmacognosy, Phytochemistry and Pharmacological Properties of Achillea millefolium L.: A Review

    Score: 6/10
    2017
    systematic_review
    0

    Ali SI, Gopalakrishnan B, Venkatesalu V

    Yarrow extracts show anti-inflammatory, antioxidant, antispasmodic and wound-healing activity in preclinical models; clinical trials are scarce.

    View source

    Yarrow (Achillea millefolium L. s.l.): a neglected panacea? A review of ethnobotany, bioactivity, and biomedical research

    Score: 5/10
    2011
    systematic_review
    0

    Applequist WL, Moerman DE

    Traditional use for wounds, fevers and menstrual complaints is extensive, but controlled clinical evidence is nearly absent.

    View source

    Biological activities of yarrow species (Achillea spp.)

    Score: 5/10
    2008
    systematic_review
    0

    Nemeth E, Bernath J

    Proazulene and essential-oil content vary widely between yarrow chemotypes and harvest conditions.

    View source

    Safety Information

    Potential Side Effects

    Allergic contact dermatitis, photosensitivity, gastrointestinal upset. Thujone raises seizure concern at high chronic doses.

    Contraindications

    Pregnancy — traditional emmenagogue and uterine stimulant use. Asteraceae allergy. Seizure disorders.

    Drug Interactions

    • Anticoagulants — theoretical additive effect
    • Sedatives — possible additive drowsiness

    Pregnancy & Breastfeeding

    Pregnancy: Likely unsafe

    Breastfeeding: Not enough evidence to judge

    Dosage Guidelines

    Dosage Used in Studies

    Consult healthcare provider

    Best Time to Take

    Before meals for digestive use

    Best Form

    Dried herb infusion, or topical preparation for wounds

    Bioavailability

    Not well characterised for the active constituents

    Dosing by Goal

    GoalDoseNotes
    Typical2-4 g dried herb as tea up to three times dailyLimit continuous internal use to a few weeks due to thujone

    Forms Compared

    Dried herb tea

    Traditional digestive and menstrual use

    Topical extract or ointment

    The application with the most supportive small-trial data

    Essential oil

    Thujone-containing; not for internal use

    Food & Timing

    Bitter action is strongest taken shortly before meals

    Medical Disclaimer

    The information provided on this website is for educational and informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or before starting any supplement regimen.

    Individual results may vary. The statements on this website have not been evaluated by the Food and Drug Administration. Products and information are not intended to diagnose, treat, cure, or prevent any disease.