Effects of ascorbic acid supplementation on serum progesterone levels in patients with a luteal phase defect
Henmi H, Endo T, Kitajima Y, Manase K, Hata H, Kudo R
Published in Fertility and Sterility, Vol. 80 (2), pp. 459-61
Methodology
Randomized controlled trial of 750 mg daily vitamin C versus no treatment in infertile women with luteal phase defect, measuring serum progesterone.
Key Findings
Serum progesterone rose significantly in the vitamin C group compared with untreated controls, with a higher pregnancy rate.
Conclusions
Vitamin C may modestly support luteal progesterone production.
Limitations
No placebo control; single small trial.
Supplements Studied
Serum progesterone rose significantly in the vitamin C group compared with untreated controls
Outcomes Measured
Serum progesterone rose significantly in the vitamin C group compared with untreated controls
Serum progesterone rose significantly in the vitamin C group compared with untreated controls, with a higher pregnancy rate
Study Details
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