Effect of pyridoxine on human hypophyseal trophic hormone release: a possible stimulation of hypothalamic dopaminergic pathway
Delitala G, Masala A, Alagna S, Devilla L
Published in Journal of Clinical Endocrinology and Metabolism, Vol. 42 (3), pp. 603-6
Methodology
Controlled endocrine study of pyridoxine administration on basal and stimulated prolactin secretion in humans.
Key Findings
Pyridoxine acutely suppressed prolactin release through dopaminergic stimulation, but the effect was short-lived and did not normalise pathological hyperprolactinaemia.
Conclusions
Vitamin B6 exerts only transient dopaminergic prolactin suppression.
Limitations
Very small, dated study; acute design only.
Supplements Studied
Pyridoxine acutely suppressed prolactin release through dopaminergic stimulation, but the effect was short-lived
Outcomes Measured
Pyridoxine acutely suppressed prolactin release through dopaminergic stimulation, but the effect was short-lived and did not normalise pathological hyperprolactinaemia
Study Details
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