Protein source tryptophan versus pharmaceutical grade tryptophan as an efficacious treatment for chronic insomnia
Hudson C, Hudson SP, Hecht T, MacKenzie J
Published in Nutritional Neuroscience, Vol. 8 (2), pp. 121-7
Methodology
Randomized controlled trial of protein-source tryptophan supplementation measuring urinary 6-sulfatoxymelatonin and sleep outcomes.
Key Findings
Tryptophan supplementation increased overnight melatonin metabolite excretion and improved sleep continuity.
Conclusions
Tryptophan availability limits endogenous melatonin synthesis in some adults.
Limitations
Small sample; older study with limited blinding detail.
Supplements Studied
Tryptophan supplementation increased overnight melatonin metabolite excretion and improved sleep continuity.
Tryptophan supplementation increased overnight melatonin metabolite excretion and improved sleep continuity.
Outcomes Measured
Tryptophan supplementation increased overnight melatonin metabolite excretion and improved sleep continuity
Tryptophan supplementation increased overnight melatonin metabolite excretion and improved sleep continuity.
Study Details
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