Treatment of outflow tract obstruction due to benign prostatic hyperplasia with the pollen extract, cernilton. A double-blind, placebo-controlled study
Buck AC, Cox R, Rees RW, Ebeling L, John A
Published in Br J Urol, Vol. 66 (4), pp. 398-404
Methodology
Double-blind, placebo-controlled trial of a 6-month course of rye grass pollen extract in 60 men with outflow obstruction due to BPH. The abstract does not describe how men were allocated.
Key Findings
Subjective improvement in 69% of men on the extract versus 30% on placebo, a statistically significant difference. Residual urine and the antero-posterior diameter of the prostate on ultrasound decreased on the extract; differences in flow rate and voided volume were not statistically significant.
Conclusions
The authors concluded the extract has a beneficial effect in BPH and may have a place in men with mild or moderate symptoms of outflow obstruction.
Limitations
Small (60 men) and old; randomisation and allocation concealment are not described in the abstract; objective flow measures were not significantly better than placebo; the dose is not given in the abstract.
Supplements Studied
statistically significant subjective improvement with Cernilton (69% of the patients) compared with placebo (30%)
Related Health Concerns
Study Details
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