Saffron (Crocus sativus L.) and major depressive disorder: a meta-analysis of randomized clinical trials
Hausenblas HA, Saha D, Dubyak PJ, Anton SD
Published in Journal of Integrative Medicine, Vol. 11 (6), pp. 377-83
Methodology
Meta-analysis of randomized controlled trials of saffron versus placebo or antidepressants for depressive symptoms including loss of interest and pleasure.
Key Findings
Saffron significantly outperformed placebo and matched standard antidepressants on depression severity including anhedonia items.
Conclusions
Saffron improves depressive symptoms that include blunted pleasure response.
Limitations
Nearly all trials conducted in Iran; small samples.
Supplements Studied
Saffron significantly outperformed placebo and matched standard antidepressants on depression severity
Outcomes Measured
Saffron significantly outperformed placebo and matched standard antidepressants on depression severity including anhedonia items
Saffron significantly outperformed placebo and matched standard antidepressants on depression severity
Saffron significantly outperformed placebo on depression severity including anhedonia items
Saffron significantly outperformed placebo and matched standard antidepressants on depression severity
Related Health Concerns
Study Details
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