Evaluation of the efficacy and safety of Tribulus terrestris in male sexual dysfunction: a prospective, randomized, double-blind, placebo-controlled clinical trial
Kamenov Z, Fileva S, Kalinov K, Jannini EA
Published in Maturitas
Methodology
Prospective, randomized, double-blind, placebo-controlled trial of Tribulus terrestris extract (Tribestan) versus placebo in men with erectile dysfunction with or without hypoactive sexual desire disorder
Key Findings
Tribulus terrestris produced statistically significant improvement over placebo on IIEF scores in men with mild to moderate erectile dysfunction, with a safety profile similar to placebo.
Conclusions
Tribulus terrestris may modestly improve erectile function in mild to moderate ED, but the effect requires replication.
Limitations
Single 12-week trial, industry-linked product, uncertain generalizability to severe ED.
Supplements Studied
Tribulus terrestris improved IIEF erectile function and desire scores versus placebo without changing testosterone
Outcomes Measured
Tribulus improved sexual desire scores versus placebo
Tribulus terrestris improved IIEF total and erectile function scores versus placebo
Related Health Concerns
Study Details
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Disclosures
Funding
Sopharma
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