Efficacy and safety of Saccharomyces boulardii in amebiasis-associated diarrhea in children
Savaş-Erdeve S, Gökay S, Dallar Y
Published in Turk J Pediatr, Vol. 51 (3), pp. 220-4
Methodology
Randomised prospective trial in 85 children with amoebiasis-associated acute diarrhoea: metronidazole alone for 10 days (n=45) or metronidazole plus S. boulardii (n=40). Outcomes were duration of acute and bloody diarrhoea, stool frequency and consistency, symptom resolution and tolerability.
Key Findings
Median duration of acute diarrhoea was 5 days without and 4.5 days with S. boulardii (p=0.965). Stool numbers and the duration of bloody diarrhoea, fever, abdominal pain and vomiting were similar. No side effects were recorded with the yeast.
Conclusions
Adding S. boulardii to metronidazole did not appear more effective than metronidazole alone; it was well tolerated.
Limitations
The abstract does not give the yeast dose, the blinding method or cyst clearance; small sample.
Supplements Studied
does not seem to be more effective than metronidazole treatment alone
Related Health Concerns
Study Details
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