Effect of resveratrol on glucose control and insulin sensitivity: a meta-analysis of 11 randomized controlled trials
Liu K, Zhou R, Wang B, Mi MT
Published in American Journal of Clinical Nutrition, Vol. 99 (6), pp. 1510-9
Methodology
Meta-analysis of randomised controlled trials of resveratrol on glucose control and insulin sensitivity, the main clinical readouts of SIRT1 activation.
Key Findings
Resveratrol significantly improved glucose control and insulin sensitivity in people with diabetes but produced no significant effect in non-diabetic participants.
Conclusions
Sirtuin-pathway effects of resveratrol are limited to metabolically impaired populations.
Limitations
Heterogeneous doses; small trials.
Supplements Studied
Resveratrol significantly improved glucose control and insulin sensitivity in people with diabetes but produced no significant effect in non-diabetic participants
Outcomes Measured
Resveratrol significantly improved glucose control and insulin sensitivity in people with diabetes but produced no significant effect in non-diabetic participants
Resveratrol significantly improved glucose control and insulin sensitivity in people with diabetes but produced no significant effect in non-diabetic participants.
Study Details
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