Results from the Xylitol for Adult Caries Trial (X-ACT)
Bader JD, Vollmer WM, Shugars DA, Gilbert GH, Amaechi BT, Brown JP, et al.
Published in J Am Dent Assoc, Vol. 144 (1), pp. 21-30
Methodology
Three-site, placebo-controlled randomised trial in caries-active adults aged 21-80 given five 1.0 g xylitol or placebo lozenges daily for 33 months.
Key Findings
Xylitol lozenges reduced the caries increment by 10 percent, less than one-third of a surface per year, which was not statistically significant. There was no dose-response effect.
Conclusions
Daily xylitol lozenges did not significantly reduce 33-month caries increment in adults at elevated risk.
Limitations
Adults only, lozenge form only, and a 5 g daily dose; results do not apply to gum or to children.
Supplements Studied
did not result in a statistically or clinically significant reduction in 33-month caries increment
Related Health Concerns
Study Details
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This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.