The Effect of Probiotic Yogurt Containing Lactobacillus rhamnosus and Bifidobacterium bifidum on Disease Activity and Disability in Patients with Systemic Lupus Erythematosus: A Randomized Controlled Trial
Banaki R, Faezi ST, Esmaeilzadeh A, Mahmoudi M, Farhadi E, Alikhani M
Published in Iran J Allergy Asthma Immunol, Vol. 24 (3), pp. 292-303
Methodology
Triple-blind randomised controlled trial in adults with SLE (SLEDAI 6 or less, stable immunosuppressant dose for 3 months): 200 g a day of probiotic yogurt containing Lactobacillus rhamnosus and Bifidobacterium bifidum, or the same yogurt without the bacteria, for 13 weeks. Outcomes: SLEDAI and the Health Assessment Questionnaire (HAQ).
Key Findings
19 patients in the probiotic group and 14 in the control group were compared. There was no significant difference in SLEDAI or HAQ disability between groups at the end of the study.
Conclusions
Probiotic yogurt did not have a significant short-term effect on disease activity or disability in SLE.
Limitations
Small, with unequal groups at analysis; participants had low disease activity, leaving little room to improve; CFU dose not stated in the abstract.
Supplements Studied
did not have a significant short-term effect on SLEDAI and disability in SLE patients
did not have a significant short-term effect on SLEDAI and disability in SLE patients
did not have a significant short-term effect on SLEDAI and disability in SLE patients
Related Health Concerns
Study Details
Access Study
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.