The effect of oat β-glucan on LDL-cholesterol, non-HDL-cholesterol and apoB for CVD risk reduction: a systematic review and meta-analysis of randomised-controlled trials

Ho HV, Sievenpiper JL, Zurbau A, Blanco Mejia S, Jovanovski E, Au-Yeung F, et al.

Published in Br J Nutr, Vol. 116 (8), pp. 1369-1382

Methodology

Systematic review and meta-analysis of randomised controlled trials of at least 3 weeks comparing oat beta-glucan-enriched diets with control diets; random-effects pooling.

Key Findings

58 trials (n=3,974). A median 3.5 g/day of oat beta-glucan lowered LDL cholesterol by 0.19 mmol/L (95% CI 0.14 to 0.23; P<0.00001), non-HDL cholesterol by 0.20 mmol/L and apoB by 0.03 g/L versus control. Heterogeneity was considerable (I2=79% for LDL).