systematic_review
    2014

    Niacinamide: mechanisms of action and its topical use in dermatology

    Wohlrab J, Kreft D

    Published in Skin Pharmacology and Physiology, Vol. 27 (6), pp. 311-5

    Key Findings

    Topical niacinamide improves barrier function, hyperpigmentation and fine lines by supporting cellular NAD+ and ceramide synthesis.

    Conclusions

    Strong mechanistic and cosmetic dermatology support.

    Limitations

    Narrative review of mostly small trials.

    Supplements Studied

    Topical niacinamide improves barrier function, hyperpigmentation and fine lines via cellular NAD+ and ceramide synthesis.

    Outcomes Measured

    Topical niacinamide improves barrier function, hyperpigmentation and fine lines.

    Topical niacinamide improves barrier function, hyperpigmentation and fine lines by supporting cellular NAD+ and ceramide synthesis.

    Study Details

    Year:2014
    Quality Score:6/10

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.